This is one of the most abundant current endocannabinoids out there, which does flow between your neurons to control the release. This is a molecule that does keep everything in balance, including your immunity, your appetite as the body needs it, and it can even play a role in sexual arousal of the body. 

Who discovered it. 

The person who discovered 2-Arachidonoglycerol, or 2-AG is someone who played a major role in the way that cannabinoids work, and it was found by a game named Dr. Raphael Meschoulam, and it’s one who found this in Israel, discovering this along with the compound of THC on the ECS. He found that 2-Ag had specific signaling aspects that came along with this, and it soon what’s called the endocannabinoids, which are cannabinoids that are within the body. His team then went to look at the different ligands that are within the tissues of animals, and that 2-AG among other ligands, did bond with the ECS receptors too. 

So what is it Exactly? 

This is a chemical which does bind directly to your ECS receptors, offering the champagnes that are necessary within specific target cells. It’s an ester that’s created with omega-6 arachidonic acid, along with glycerol that comes from arachidonic acid. This is something that’s a lipid (otherwise known as fats) that offer messages within your ECS. 

Because it uses these fatty acids, various dietary changes do change the “tone” of your ECS. The 2AG fluids offer the status as one of the most abundant kinds of endocannabinoids in the brain, and it’s considered the full agonist amongst your ECS receptors too. That means when it does bind to the CB1 and CB2 receptors, it gets fully activated.  Anandamide is a partial agonist of this, so the results are quite limited. 

The functions 

This is one that’s very important for your central nervous system, and the immune system, due to what the body needs to break it down to modulate. For the CNS, it’s basically responsible for the release  of the 2AG receptors, so it’s a big responsibility for it, since it’s basically how we feel, look, and perceive various realities. 

There are a few ways for you to look at this. The main way is that the neurons do send various signals via impulses, which do result in neurotransmitter releases. When this recaches what’s called the presynaptic neuron, it does prompt the release of this, and then it binds to your postsynaptic neurons. 

This does work on retrograde ways, so it goes back across the cleft, which is then against the normal flow.  This is because it allows for postsynaptic cells to control the traffic of it, causing excitation of this. 

As for the immune system, it offers balance to this immune system by possessing both the CB1 and the CB2 receptors, it controls and modulates these. 

This includes the following: 

• Your b cells 
• Your natural killer cells 
• The monocytes 

This is something that dampens the firing when needed, and it then prevents your immunity from going crazy. 

It also works to help with stimulating your appetite, which is partially responsible for the “munchies” you get when you have cannabis.  It can control the food intake, so that’s why you may eat after smoking. Finally, it controls sexual function, and it can help cap the sexual desire feelings. According to a study that looked at the concentrations of this, it wsa found that endocannabinoids gatekeep the feelings of your sexual desire as it arises, and they also do help to temporarily look at different feelings as well.